Study of vitamin D receptor gene polymorphisms in a cohort of myocardial infarction patients with coronary artery disease.

ABSTRACT:

Background

Vitamin D deficiency is associated with cardiovascular diseases, including coronary artery diseases (CAD). As vitamin D manifests its biological function through its vitamin D receptor (VDR), VDR gene polymorphisms potentially affect VDR functionality and vitamin D activity. Therefore, the objective of this study was to analyze three well-studied VDR gene polymorphisms-Fok1 (rs2228570), BsmI (rs1544410) and Taq1 (rs731236)-in a cohort of CAD patients after acute myocardial infarction.

Methods

In the presented cross-sectional study, 155 participants with CAD after acute myocardial infarction and 104 participants in a control group without CAD were enrolled. The participants in both groups were Caucasians of European origin. The genotyping of VDR polymorphisms rs222

SUBMITTER: Raljevic D 

PROVIDER: S-EPMC8052753 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature