NGS-guided precision oncology in metastatic breast and gynecological cancer: first experiences at the CCC Munich LMU.

ABSTRACT:

Purpose

Comprehensive genomic profiling identifying actionable molecular alterations aims to enable personalized treatment for cancer patients. The purpose of this analysis was to retrospectively assess the impact of personalized recommendations made by a multidisciplinary tumor board (MTB) on the outcome of patients with breast or gynecological cancers, who had progressed under standard treatment. Here, first experiences of our Comprehensive Cancer Center Molecular Tumor Board are reported.

Methods

All patients were part of a prospective local registry. 95 patients diagnosed with metastatic breast cancer or gynecological malignancies underwent extended molecular profiling. From May 2017 through March 2019, the MTB reviewed all clinical cases considering tumor profile and ev

SUBMITTER: Sultova E 

PROVIDER: S-EPMC8053190 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature