Relationship between Hearing Loss and Dementia Differs According to the Underlying Mechanism.

ABSTRACT:

Background and purpose

The associations between hearing loss (HL) and the mechanisms underlying cognitive impairment (CI) remain unclear. We evaluated the effects of clinical factors, vascular magnetic resonance imaging (MRI) markers, and CI mechanisms on HL.

Methods

In total, 112 patients with CI (59% demented) and subjective HL prospectively underwent MRI, amyloid positron-emission tomography (PET), hearing evaluations, and neuropsychological tests including a language comprehension test. Patients were categorized into pure-Alzheimer's disease-related CI (ADCI), pure-Lewy-body disease-related CI (LBCI), mixed-ADCI/LBCI, and non-ADCI/LBCI groups based on clinical features and PET biomarkers.

Results

The risk of peripheral HL [defined as a pure-tone average (PTA) thre

SUBMITTER: Jung J 

PROVIDER: S-EPMC8053549 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature