Coagulopathy and its effect on treatment and mortality in patients with traumatic intracranial hemorrhage.

ABSTRACT:

Background

The role of coagulopathy in patients with traumatic brain injury has remained elusive. In the present study, we aim to assess the prevalence of coagulopathy in patients with traumatic intracranial hemorrhage, their clinical features, and the effect of coagulopathy on treatment and mortality.

Methods

An observational, retrospective single-center cohort of consecutive patients with traumatic intracranial hemorrhage treated at Helsinki University Hospital between 01 January and 31 December 2010. We compared clinical and radiological parameters in patients with and without coagulopathy defined as drug- or disease-induced, i.e., antiplatelet or anticoagulant medication at a therapeutic dose, thrombocytopenia (platelet count < 100 E9/L), international normalized ratio >

SUBMITTER: Kinnunen J 

PROVIDER: S-EPMC8053656 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature