Hypofractionated radiotherapy in the real-world setting: An international ESTRO-GIRO survey.

ABSTRACT:

Background and purpose

Multiple large trials have established the non-inferiority of hypofractionated radiotherapy compared to conventional fractionation. This study will determine real-world hypofractionation adoption across different geographic regions for breast, prostate, cervical cancer, and bone metastases, and identify barriers and facilitators to its use.

Materials and methods

An anonymous, electronic survey was distributed from January 2018 through January 2019 to radiation oncologists through the ESTRO-GIRO initiative. Predictors of hypofractionation were identified in univariable and multivariable regression analyses.

Results

2316 radiation oncologists responded. Hypofractionation was preferred in node-negative breast cancer following lumpectomy (82·2% vs.

SUBMITTER: Rodin D 

PROVIDER: S-EPMC8053676 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature