Diffusion MRI tractography filtering techniques change the topology of structural connectomes.

ABSTRACT: Objective.The use of non-invasive techniques for the estimation of structural brain networks (i.e. connectomes) opened the door to large-scale investigations on the functioning and the architecture of the brain, unveiling the link between neurological disorders and topological changes of the brain network. This study aims at assessing if and how the topology of structural connectomes estimated non-invasively with diffusion MRI is affected by the employment of tractography filtering techniques in structural connectomic pipelines. Additionally, this work investigates the robustness of topological descriptors of filtered connectomes to the common practice of density-based thresholding.Approach.We investigate the changes in global efficiency, characteristic path length, modularit

SUBMITTER: Frigo M 

PROVIDER: S-EPMC8053736 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature