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Effectiveness of potential antiviral treatments in COVID-19 transmission control: a modelling study.


ABSTRACT:

Background

Novel coronavirus disease 2019 (COVID-19) causes an immense disease burden. Although public health countermeasures effectively controlled the epidemic in China, non-pharmaceutical interventions can neither be maintained indefinitely nor conveniently implemented globally. Vaccination is mainly used to prevent COVID-19, and most current antiviral treatment evaluations focus on clinical efficacy. Therefore, we conducted population-based simulations to assess antiviral treatment effectiveness among different age groups based on its clinical efficacy.

Methods

We collected COVID-19 data of Wuhan City from published literature and established a database (from 2 December 2019 to 16 March 2020). We developed an age-specific model to evaluate the effectiveness of antiviral

SUBMITTER: Lin SN 

PROVIDER: S-EPMC8054260 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature