Single-cell resolution of lineage trajectories in the Arabidopsis stomatal lineage and developing leaf.

ABSTRACT: Dynamic cell identities underlie flexible developmental programs. The stomatal lineage in the Arabidopsis leaf epidermis features asynchronous and indeterminate divisions that can be modulated by environmental cues. The products of the lineage, stomatal guard cells and pavement cells, regulate plant-atmosphere exchanges, and the epidermis as a whole influences overall leaf growth. How flexibility is encoded in development of the stomatal lineage and how cell fates are coordinated in the leaf are open questions. Here, by leveraging single-cell transcriptomics and molecular genetics, we uncovered models of cell differentiation within Arabidopsis leaf tissue. Profiles across leaf tissues identified points of regulatory congruence. In the stomatal lineage, single-cell resolution resolved under

SUBMITTER: Lopez-Anido CB 

PROVIDER: S-EPMC8054824 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature