Corticosteroids in COVID-19 and non-COVID-19 ARDS: a systematic review and meta-analysis.

ABSTRACT:

Purpose

Corticosteroids are now recommended for patients with severe COVID-19 including those with COVID-related ARDS. This has generated renewed interest regarding whether corticosteroids should be used in non-COVID ARDS as well. The objective of this study was to summarize all RCTs examining the use of corticosteroids in ARDS.

Methods

The protocol of this study was pre-registered on PROSPERO (CRD42020200659). We searched online databases including MEDLINE, EMBASE, CDC library of COVID research, CINAHL, and COCHRANE. We included RCTs that compared the effect of corticosteroids to placebo or usual care in adult patients with ARDS, including patients with COVID-19. Three reviewers abstracted data independently and in duplicate using a pre-specified standardized form. We asses

SUBMITTER: Chaudhuri D 

PROVIDER: S-EPMC8054852 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature