Chlamydia pneumoniae and chronic asthma: Updated systematic review and meta-analysis of population attributable risk.

ABSTRACT:

Background

Chlamydia pneumoniae (Cp) is an obligate intracellular human respiratory pathogen producing persisting lung infection with a plausible link to asthma pathogenesis. The population attributable risk of potentially treatable Cp infection in asthma has not been reported.

Methods

The author searched from 2000 to 2020 inclusive for previously un-reviewed and new cross sectional and prospective controlled studies of Cp biomarkers and chronic asthma in both children and adults. Qualitative descriptive results and quantitative estimates of population attributable risk for selected biomarkers (specific IgG, IgA and IgE) are presented.

Findings

No large, long-term prospective population-based studies of Cp infection and asthma were identified. About half of case-contr

SUBMITTER: Hahn DL 

PROVIDER: S-EPMC8055030 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature