Cortex-Wide Dynamics of Intrinsic Electrical Activities: Propagating Waves and Their Interactions.

ABSTRACT: Cortical circuits generate patterned activities that reflect intrinsic brain dynamics that lay the foundation for any, including stimuli-evoked, cognition and behavior. However, the spatiotemporal organization properties and principles of this intrinsic activity have only been partially elucidated because of previous poor resolution of experimental data and limited analysis methods. Here we investigated continuous wave patterns in the 0.5-4 Hz (delta band) frequency range on data from high-spatiotemporal resolution optical voltage imaging of the upper cortical layers in anesthetized mice. Waves of population activities propagate in heterogeneous directions to coordinate neuronal activities between different brain regions. The complex wave patterns show characteristics of both stereotypy an

SUBMITTER: Liang Y 

PROVIDER: S-EPMC8055070 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature