Fatal and Nonfatal Events Within 14 days After Early, Intensive Mobilization Poststroke.

ABSTRACT:

Objective

This tertiary analysis from A Very Early Rehabilitation Trial (AVERT) examined fatal and nonfatal serious adverse events (SAEs) at 14 days.

Method

AVERT was a prospective, parallel group, assessor blinded, randomized international clinical trial comparing mobility training commenced <24 hours poststroke, termed very early mobilization (VEM), to usual care (UC). Primary outcome was assessed at 3 months. Patients with ischemic or hemorrhagic stroke within 24 hours of onset were included. Treatment with thrombolytics was allowed. Patients with severe premorbid disability or comorbidities were excluded. Interventions continued for 14 days or hospital discharge if less. The primary early safety outcome was fatal SAEs within 14 days. Secondary outcomes were nonfatal SAEs

SUBMITTER: Bernhardt J 

PROVIDER: S-EPMC8055346 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature