Prognostic implications of pericardial and pleural effusion in patients with cardiac amyloidosis.

ABSTRACT:

Background

Pericardial and pleural effusion are common findings in patients with cardiac amyloidosis (CA). It is not known, whether effusions correlate with right ventricular (RV) function in these patients. Furthermore, data on the prognostic significance of pleural and pericardial effusion in CA is scarce.

Methods

Patients with transthyretin (ATTR) and light chain (AL) CA were included in a clinical registry. All patients underwent transthoracic echocardiography at baseline. The presence of pericardial and pleural effusion was determined in every patient. The clinical endpoint was defined as cardiac death or heart failure hospitalization.

Results

In total, 143 patients were analysed. Of these, 85 patients were diagnosed with ATTR and 58 patients with AL. Twenty-four

SUBMITTER: Binder C 

PROVIDER: S-EPMC8055634 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature