Physician-guided, hybrid genetic testing exerts promising effects on health-related behavior without compromising quality of life.

ABSTRACT: Genetic risk analysis is increasingly in demand by participants. Hybrid genetic testing has the advantage over direct to consumer testing by involving a physician who guides the process and offers counseling after receiving the results. The objective of this study was to determine whether a structured physician moderated primary preventive, hybrid genetic risk assessment enhanced counseling program leads to improvement in lifestyle and does not impair quality of life. Risk genes for malignant, cardiovascular, coagulation, storage diseases and pharmacogenetics (> 100 genes) were tested. Screening, consultation and genetic counseling embedded in a primary/secondary prevention check-up program for executives of surrounding companies took place in a single center in Germany. Follow-up included

SUBMITTER: Schricker S 

PROVIDER: S-EPMC8055666 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature