Study on the Influence of mRNA, the Genetic Language, on Protein Folding Rates.

ABSTRACT: Many works have reported that protein folding rates are influenced by the characteristics of amino acid sequences and protein structures. However, few reports on the problem of whether the corresponding mRNA sequences are related to the protein folding rates can be found. An mRNA sequence is regarded as a kind of genetic language, and its vocabulary and phraseology must provide influential information regarding the protein folding rate. In the present work, linear regressions on the parameters of the vocabulary and phraseology of mRNA sequences and the corresponding protein folding rates were analyzed. The results indicated that D ₂ (the adjacent base-related information redundancy) values and the GC content values of the corresponding mRNA sequences exhibit significant n

SUBMITTER: Li R 

PROVIDER: S-EPMC8056030 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature