Constructing and analysing dynamic models with modelbase v1.2.3: a software update.

ABSTRACT:

Background

Computational mathematical models of biological and biomedical systems have been successfully applied to advance our understanding of various regulatory processes, metabolic fluxes, effects of drug therapies, and disease evolution and transmission. Unfortunately, despite community efforts leading to the development of SBML and the BioModels database, many published models have not been fully exploited, largely due to a lack of proper documentation or the dependence on proprietary software. To facilitate the reuse and further development of systems biology and systems medicine models, an open-source toolbox that makes the overall process of model construction more consistent, understandable, transparent, and reproducible is desired.

Results and discussion

We provid

SUBMITTER: van Aalst M 

PROVIDER: S-EPMC8056244 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature