EVA1B to Evaluate the Tumor Immune Microenvironment and Clinical Prognosis in Glioma.

ABSTRACT:

Background

Previous research indicated that the tumor cells and microenvironment interactions are critical for the immunotherapeutic response. However, predicting the clinical response to immunotherapy remains a dilemma for clinicians. Hence, this study aimed to investigate the associations between EVA1B expression and prognosis and tumor-infiltrating immune cells in glioma.

Methods

Firstly, we detected the EVA1B expression in glioma tissues through biological databases. The chi-squared test, Kaplan-Meier, and univariate and multivariate Cox regression analyses were used to analyze the clinical significance of EVA1B expression. The correlation between EVA1B expression and levels of tumor-infiltrating immune cells in glioma tissues was investigated

SUBMITTER: Qu S 

PROVIDER: S-EPMC8056259 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature