FINDER: an automated software package to annotate eukaryotic genes from RNA-Seq data and associated protein sequences.

ABSTRACT:

Background

Gene annotation in eukaryotes is a non-trivial task that requires meticulous analysis of accumulated transcript data. Challenges include transcriptionally active regions of the genome that contain overlapping genes, genes that produce numerous transcripts, transposable elements and numerous diverse sequence repeats. Currently available gene annotation software applications depend on pre-constructed full-length gene sequence assemblies which are not guaranteed to be error-free. The origins of these sequences are often uncertain, making it difficult to identify and rectify errors in them. This hinders the creation of an accurate and holistic representation of the transcriptomic landscape across multiple tissue types and experimental conditions. Therefore, to gauge the exte

SUBMITTER: Banerjee S 

PROVIDER: S-EPMC8056616 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature