Retrograde inferior vena caval perfusion for total aortic arch replacement surgery: a randomized pilot study.

ABSTRACT:

Objectives

Antegrade cerebral perfusion (ACP) under moderate hypothermic circulatory arrest is used during total aortic arch replacement surgery (TARS) in patients with acute type A aortic dissection, but it is associated with high mortality and morbidity. We hypothesized that combining ACP with retrograde inferior vena caval perfusion (RIVP) improves outcomes.

Methods

This pilot study was prospective, randomized, controlled and assessor-blinded. Patients scheduled for TARS were randomly treated with either ACP or RIVP + ACP. The primary outcome was a composite of mortality and major complications including paraplegia, postoperative renal failure, severe liver dysfunction, and gastrointestinal complications. Secondary outcomes included neurological complications, length of i

SUBMITTER: Lin J 

PROVIDER: S-EPMC8056667 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature