Risk prediction in medically treated chronic thromboembolic pulmonary hypertension.

ABSTRACT:

Background

At present, there is no generally accepted comprehensive prognostic risk prediction model for medically treated chronic thromboembolic pulmonary hypertension (CTEPH) patients.

Methods

Consecutive medically treated CTEPH patients were enrolled in a national multicenter prospective registry study from August 2009 to July 2018. A multivariable Cox proportional hazards model was utilized to derive the prognostic model, and a simplified risk score was created thereafter. Model performance was evaluated in terms of discrimination and calibration, and compared to the Swedish/COMPERA risk stratification method. Internal and external validation were conducted to validate the model performance.

Results

A total of 432 patients were enrolled. During a median follow-up

SUBMITTER: Quan R 

PROVIDER: S-EPMC8056726 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature