Single isocenter treatment planning techniques for stereotactic radiosurgery of multiple cranial metastases.

ABSTRACT:

Background and purpose

Whole brain radiation therapy use has decreased in favor of stereotactic radiosurgery (SRS) for the treatment of multiple brain metastases due to reduced neurotoxicity. Here we compare two single isocenter radiosurgery planning techniques, volumetric modulated arc therapy (VMAT) and dynamic conformal arcs (DCA) in terms of their dosimetric and delivery performance.

Materials and methods

Sixteen patients with 2- 18 brain metastases (total 103; median 4) previously treated with single fraction SRS were replanned for multiple lesion single isocenter treatments using VMAT and DCA using different treatment planning systems for each and three different plan geometries for DCA. Plans were evaluated using the Paddick conformity index, normal tissue V_12Gy<

SUBMITTER: Velten C 

PROVIDER: S-EPMC8058031 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature