Psychosocial outcomes following germline multigene panel testing in an ethnically and economically diverse cohort of patients.

ABSTRACT:

Background

Little is known about the psychological outcomes of germline multigene panel testing, particularly among diverse patients and those with moderate-risk pathogenic variants (PVs).

Methods

Study participants (N = 1264) were counseled and tested with a 25- or 28-gene panel and completed a 3-month postresult survey including the Multidimensional Impact of Cancer Risk Assessment (MICRA).

Results

The mean age was 52 years, 80% were female, and 70% had cancer; 45% were non-Hispanic White, 37% were Hispanic, 10% were Asian, 3% were Black, and 5% had another race/ethnicity. Approximately 28% had a high school education or less, and 23% were non-English-speaking. The genetic test results were as follows: 7% had a high-risk PV, 6% had a moderate-risk PV, 35% had a vari

SUBMITTER: Culver JO 

PROVIDER: S-EPMC8058169 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature