Psychometric Properties of the Clinical Dementia Rating Scale Sum of Boxes in Parkinson's Disease.

ABSTRACT:

Background

A composite measure that assesses both cognitive and functional abilities in Parkinson's disease (PD) would be useful for diagnosing mild cognitive impairment (MCI) and PD dementia (PDD) and as an outcome measure in randomized controlled trials. The Clinical Dementia Rating Scale Sum of Boxes (CDR-SOB) was designed to assess both cognition and basic-instrumental activities of daily living in Alzheimer's disease but has not yet been validated in PD.

Objective

To validate the CDR-SOB as a composite cognitive-functional measure for PD patients, as well as to assess its sensitivity to change.

Methods

The CDR-SOB and a comprehensive cognitive and functional battery was administered to 101 PD patients at baseline (39 normal cognition [NC], 41 MCI and 21 PDD by ex

SUBMITTER: Gallagher J 

PROVIDER: S-EPMC8058172 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature