A comparison of methods in estimating population attributable risk for colorectal cancer in the United States.

ABSTRACT: Population attributable risk (PAR) is becoming more widely used for quantifying preventability of cancer. However, its estimations have had a wide range, leading to questions about the true preventability. Our study aimed to compare the two PAR estimation methods (ie, literature-based method and low-risk method) for colorectal cancer (CRC) in the US population based on the same set of modifiable risk factors: physical activity, body mass index, alcoholic drinks, red meat, processed meat, dietary fiber, dietary calcium and cigarette smoking. For the literature-based method, 65% and 53%, and for the low-risk method, 62% and 49% of CRC cases for males and females, respectively, were attributable to the eight dietary and lifestyle risk factors. Additional sensitivity analyses were conducted wi

SUBMITTER: Kim H 

PROVIDER: S-EPMC8058283 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature