Vestibular Organ and Cochlear Implantation-A Synchrotron and Micro-CT Study.

ABSTRACT: Background: Reports vary on the incidence of vestibular dysfunction and dizziness in patients following cochlear implantation (CI). Disequilibrium may be caused by surgery at the cochlear base, leading to functional disturbances of the vestibular receptors and endolymphatic duct system (EDS) which are located nearby. Here, we analyzed the three-dimensional (3D) anatomy of this region, aiming to optimize surgical approaches to limit damage to the vestibular organ. Material and Methods: A total of 22 fresh-frozen human temporal bones underwent synchrotron radiation phase-contrast imaging (SR-PCI). One temporal bone underwent micro-computed tomography (micro-CT) after fixation and staining with Lugol's iodine solution (I₂KI) to increase tissue contrast. We used volume

SUBMITTER: Li H 

PROVIDER: S-EPMC8058461 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature