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Ribbon: intuitive visualization for complex genomic variation.

ABSTRACT:

Summary

Ribbon is an alignment visualization tool that shows how alignments are positioned within both the reference and read contexts, giving an intuitive view that enables a better understanding of structural variants and the read evidence supporting them. Ribbon was born out of a need to curate complex structural variant calls and determine whether each was well supported by long-read evidence, and it uses the same intuitive visualization method to shed light on contig alignments from genome-to-genome comparisons.

Availability and implementation

Ribbon is freely available online at http://genomeribbon.com/ and is open-source at https://github.com/marianattestad/ribbon.

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Nattestad M

PROVIDER: S-EPMC8058763 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Ribbon: intuitive visualization for complex genomic variation.

Nattestad Maria M Aboukhalil Robert R Chin Chen-Shan CS Schatz Michael C MC

Bioinformatics (Oxford, England) 20210401 3

<h4>Summary</h4>Ribbon is an alignment visualization tool that shows how alignments are positioned within both the reference and read contexts, giving an intuitive view that enables a better understanding of structural variants and the read evidence supporting them. Ribbon was born out of a need to curate complex structural variant calls and determine whether each was well supported by long-read evidence, and it uses the same intuitive visualization method to shed light on contig alignments from ...[more]

PMID: 32766814

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