HPV infection and bacterial microbiota in the semen from healthy men.

ABSTRACT:

Background

Aberrant microbiota composition has been linked to disease development at numerous anatomical sites. Microbiota changes in reaction to viral infections, such as human papillomavirus (HPV), have been investigated almost exclusively in the female reproductive tract. However, HPV infection may also affect male health by reducing semen quality and fertility. The aim of this study was to investigate whether present HPV DNA is associated with detectable changes in semen bacterial microbiota composition and diversity.

Methods

This study relied on stored semen samples from 31 fertile healthy men who participated in the Finnish family HPV Study during the years 1998-2001. DNA was extracted from semen with PCR template preparation kit. HPV was genotyped using Luminex-based

SUBMITTER: Tuominen H 

PROVIDER: S-EPMC8059035 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature