Effect of different thresholds for CT perfusion volumetric analysis on estimated ischemic core and penumbral volumes.

ABSTRACT:

Purpose

This single-center study compared three threshold settings for automated analysis of the ischemic core (IC) and penumbral volumes using computed tomographic perfusion, and their accuracy for predicting final infarct volume (FIV) in patients with anterior circulation acute ischemic stroke (AIS).

Methods

Fifty-two consecutive AIS patients undergoing mechanical thrombectomy (November 2015-March 2018) were included. Perfusion images were retrospectively analyzed using a single CT Neuro perfusion application (syngo.via 4.1, Siemens Healthcare GmbH). Three threshold values (S1-S3) were derived from another commercial package (RAPID; iSchema View) (S1), up-to-date syngo.via default values (S2), and adapted values for syngo.via from a reference study (S3). The results were c

SUBMITTER: Karhi S 

PROVIDER: S-EPMC8059822 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature