Phylogenetic molecular evolution and recombination analysis of complete genome of human parechovirus in Thailand.

ABSTRACT: Human parechovirus (HPeV), which is a member of the Picornavirus group of viruses, is a pathogen that is reported to be associated with manifestations that include respiratory tract involvement, gastroenteritis, sepsis-like symptom, and central nervous system complication. Until now, nineteen genotypes have been identified. The lack of proofreading property of viral RNA-dependent RNA polymerase (RdRp) together with recombination among the intra- and inter-genotypes of the virus results in high diversity. However, data specific to the molecular evolutionary perspective of the complete genome of HPeV remains limited. This study aimed to analyze the phylogenetic, molecular evolution, and recombination characteristics of the complete genome of HPeV strains isolated in Thailand during 2009-2012

SUBMITTER: Chieochansin T 

PROVIDER: S-EPMC8060412 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature