Human OMICs and Computational Biology Research in Africa: Current Challenges and Prospects.

ABSTRACT: Following the publication of the first human genome, OMICs research, including genomics, transcriptomics, proteomics, and metagenomics, has been on the rise. OMICs studies revealed the complex genetic diversity among human populations and challenged our understandings of genotype-phenotype correlations. Africa, being the cradle of the first modern humans, is distinguished by a large genetic diversity within its populations and rich ethnolinguistic history. However, the available human OMICs tools and databases are not representative of this diversity, therefore creating significant gaps in biomedical research. African scientists, students, and publics are among the key contributors to OMICs systems science. This expert review examines the pressing issues in human OMICs research, education,

SUBMITTER: Hamdi Y 

PROVIDER: S-EPMC8060717 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature