Cardiovascular Biomarkers in the Early Discrimination of Type 2 Myocardial Infarction.

ABSTRACT:

Importance

Rapid and accurate noninvasive discrimination of type 2 myocardial infarction (T2MI), which is because of a supply-demand mismatch, from type 1 myocardial infarction (T1MI), which arises via plaque rupture, is essential, because treatment differs substantially. Unfortunately, this is a major unmet clinical need, because even high-sensitivity cardiac troponin (hs-cTn) measurement provides only modest accuracy.

Objective

To test the hypothesis that novel cardiovascular biomarkers quantifying different pathophysiological pathways involved in T2MI and/or T1MI may aid physicians in the rapid discrimination of T2MI vs T1MI.

Design, setting, and participants

This international, multicenter prospective diagnostic study was conducted in 12 emergency departments in 5

SUBMITTER: Nestelberger T 

PROVIDER: S-EPMC8060883 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature