Identifying key questions in the ecology and evolution of cancer.

ABSTRACT: The application of evolutionary and ecological principles to cancer prevention and treatment, as well as recognizing cancer as a selection force in nature, has gained impetus over the last 50 years. Following the initial theoretical approaches that combined knowledge from interdisciplinary fields, it became clear that using the eco-evolutionary framework is of key importance to understand cancer. We are now at a pivotal point where accumulating evidence starts to steer the future directions of the discipline and allows us to underpin the key challenges that remain to be addressed. Here, we aim to assess current advancements in the field and to suggest future directions for research. First, we summarize cancer research areas that, so far, have assimilated ecological and evolutionary princip

SUBMITTER: Dujon AM 

PROVIDER: S-EPMC8061275 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature