The role of recipient myosteatosis in graft and patient survival after deceased donor liver transplantation.

ABSTRACT:

Background

Myosteatosis is associated with perioperative outcomes in orthotopic liver transplantation (OLT). Here, we investigated the effects of body composition and myosteatosis on long-term graft and patient survival following OLT.

Methods

Clinical data from 225 consecutive OLT recipients from a prospective database were retrospectively analysed (May 2010 to December 2017). Computed tomography-based lumbar skeletal muscle index (SMI) (muscle mass) and mean skeletal muscle radiation attenuation (SM-RA) (myosteatosis) were calculated using a segmentation tool (3D Slicer). Patients with low skeletal muscle mass (low SMI) and myosteatosis (low SM-RA) were identified using predefined and validated cut-off values.

Results

The mean donor and recipient age was 55 ± 16 and

SUBMITTER: Czigany Z 

PROVIDER: S-EPMC8061365 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature