How gait influences frailty models and health-related outcomes in clinical-based and population-based studies: a systematic review.

ABSTRACT: Aging is often associated with a decline in physical function that eventually leads to loss of autonomy in activities of daily living (ADL). Walking is a very common ADL, important for main determinants of quality of life in older age, and it requires the integration of many physiological systems. Gait speed has been described as the 'sixth vital sign' because it is a core indicator of health and function in aging and disease. We reviewed original studies up to June 2020 that assessed frailty in both longitudinal and cross-sectional observational studies, paying particular attention to how gait is measured in older population and how the gait parameter adopted may influence the estimated frailty models and the health-related outcomes of the various studies (i.e. clinical, cognitive, physic

SUBMITTER: Bortone I 

PROVIDER: S-EPMC8061366 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature