Surface Potential-Controlled Oscillation in FET-Based Biosensors.

ABSTRACT: Field-effect transistor (FET)-based biosensors have garnered significant attention for their label-free electrical detection of charged biomolecules. Whereas conventional output parameters such as threshold voltage and channel current have been widely used for the detection and quantitation of analytes of interest, they require bulky instruments and specialized readout circuits, which often limit point-of-care testing applications. In this study, we demonstrate a simple conversion method that transforms the surface potential into an oscillating signal as an output of the FET-based biosensor. The oscillation frequency is proposed as a parameter for FET-based biosensors owing to its intrinsic advantages of simple and compact implementation of readout circuits as well as high compatibility wi

SUBMITTER: Kim JH 

PROVIDER: S-EPMC8061884 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature