Fiberoptic array for multiple channel infrared neural stimulation of the brain.

ABSTRACT: Significance: We present a new optical method for modulating cortical activity in multiple locations and across multiple time points with high spatial and temporal precision. Our method uses infrared light and does not require dyes or transgenic modifications. It is compatible with a number of other stimulation and recording techniques. Aim: Infrared neural stimulation (INS) has been largely confined to single point stimuli. In this study, we expand upon this approach and develop a rapidly switched fiber array capable of generation of stimulus patterns. Our prototype is capable of stimulating at nine separate locations but is easily scalable. Approach: Our device is made of commercially available components: a solid-state infrared laser, a piezoelectric fiber coupled o

SUBMITTER: Chernov MM 

PROVIDER: S-EPMC8062107 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature