Computational and experimental mechanical performance of a new everolimus-eluting stent purpose-built for left main interventions.

ABSTRACT: Left main (LM) coronary artery bifurcation stenting is a challenging topic due to the distinct anatomy and wall structure of LM. In this work, we investigated computationally and experimentally the mechanical performance of a novel everolimus-eluting stent (SYNERGY MEGATRON) purpose-built for interventions to large proximal coronary segments, including LM. MEGATRON stent has been purposefully designed to sustain its structural integrity at higher expansion diameters and to provide optimal lumen coverage. Four patient-specific LM geometries were 3D reconstructed and stented computationally with finite element analysis in a well-validated computational stent simulation platform under different homogeneous and heterogeneous plaque conditions. Four different everolimus-eluting stent designs (9

SUBMITTER: Samant S 

PROVIDER: S-EPMC8062511 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature