Prolonged Intubation in Patients With Prior Cerebrovascular Disease and COVID-19.

ABSTRACT: Objectives: Patients with comorbidities are at increased risk for poor outcomes in COVID-19, yet data on patients with prior neurological disease remains limited. Our objective was to determine the odds of critical illness and duration of mechanical ventilation in patients with prior cerebrovascular disease and COVID-19. Methods: A observational study of 1,128 consecutive adult patients admitted to an academic center in Boston, Massachusetts, and diagnosed with laboratory-confirmed COVID-19. We tested the association between prior cerebrovascular disease and critical illness, defined as mechanical ventilation (MV) or death by day 28, using logistic regression with inverse probability weighting of the propensity score. Among intubated patients, we estimated the cumulative inci

SUBMITTER: Mukerji SS 

PROVIDER: S-EPMC8062773 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature