The Impact of Asthma and Chronic Obstructive Pulmonary Disease (COPD) on Patient-Reported Outcomes in Systemic Lupus Erythematosus (SLE).

ABSTRACT:

Background

Risk of asthma and chronic obstructive pulmonary disease (COPD) may be elevated in systemic lupus erythematosus (SLE), but little research has studied the impact of these conditions on SLE outcomes. We examined prevalence, incidence, and impact of self-reported asthma and COPD in two US-based SLE cohorts (FORWARD and Lupus Outcomes Study [LOS]).

Methods

Prevalence of asthma and COPD were defined as presence of conditions at individuals' first interviews; incidence was defined as new reports over the next 3 years. Cross-sectional associations of asthma/COPD with patient-reported outcomes (PROs) and longitudinal analyses associations with asthma/COPD at entry with PROs 3 years later were examined.

Results

In FORWARD, 19.8% and 8.3% participants reported asthm

SUBMITTER: Katz P 

PROVIDER: S-EPMC8063140 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature