Development of recombinase polymerase amplification assays for rapid and visual detection of canine distemper virus infecting giant panda.

ABSTRACT:

Background

Canine distemper virus (CDV) is an enveloped negative-strand RNA virus that exhibits a high mutation rate and continuously expands the range of hosts. Notably, CDV has infected giant panda with spill over from viral reservoirs in canines. Giant pandas (Ailuropoda melanoleuca), especially captive pandas, are known to be susceptible to natural infection with CDV. The high fatality rate of CDV poses a serious threat to the safety of the giant panda population. However, vaccines or drugs for canine distemper in giant pandas have not been developed to date. Therefore, a rapid test that can achieve accurate onsite detection of CDV is important to enable the timely implementation of control measures. In this study, we established a nucleic acid visualization assay for targeting

SUBMITTER: Huang P 

PROVIDER: S-EPMC8063184 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature