Drug Repurposing Approach, Potential Drugs, and Novel Drug Targets for COVID-19 Treatment.

ABSTRACT: Novel coronavirus first appeared in Wuhan, China, in December 2019, and it speedily expanded globally. Some medications which are used to treat other diseases seem to be effective in treating COVID-19 even without explicit support. The existing drugs that are summarized in this review primarily focused on therapeutic agents that possessed activity against other RNA viruses such as MERS-CoV and SARS-CoV. Drug repurposing or repositioning is a promising field in drug discovery that identifies new therapeutic opportunities for existing drugs such as corticosteroids, RNA-dependent RNA polymerase inhibitors, interferons, protease inhibitors, ivermectin, melatonin, teicoplanin, and some others. A search for new drug/drug targets is underway. Thus, blocking coronavirus structural protein, targeti

SUBMITTER: Kifle ZD 

PROVIDER: S-EPMC8063850 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature