A Novel Gene vp0610 Negatively Regulates Biofilm Formation in Vibrio parahaemolyticus.

ABSTRACT: Vibrio parahaemolyticus is an important foodborne pathogen and its biofilm formation ability facilitates its colonization and persistence in foods by protecting it from stresses including environmental variation and antibiotic exposure. Several important proteins are involved in biofilm formation; however, the identity and function of many remain unknown. In this study, we discovered a hypothetical protein, VP0610 that negatively regulates biofilm formation in Vibrio parahaemolyticus, and we found that the loss of vp0610 typically results in pleiotropic phenotypes that contribute toward promoting biofilm formation, including significantly increased insoluble exopolysaccharide production and swimming motility, decreased soluble exopolysaccharide production, and decrease

SUBMITTER: Jiang F 

PROVIDER: S-EPMC8064395 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature