Do cholesterol levels and continuity of statin use affect colorectal cancer incidence in older adults under 75 years of age?

ABSTRACT:

Introduction

Colorectal cancer(CRC) is 3rd most common cancer and has a relatively high mortality rate. Currently, the relationships between CRC and serum cholesterol or statin treatment, especially in older adults under 75 years of age, remain questionable due to a lack of data. The present study evaluated the association between serum cholesterol levels and statin treatment continuity and CRC risk in older adults under 75 years of age.

Methods

This study used senior cohort data obtained from the National Health Insurance Service of South Korea. The selected cohort contains 131,266 participants who were enrolled from 2009 to 2011 and followed for up to 5 years. Serum cholesterol levels were classified as categorical variables, and continuity of statin treatment was evaluate

SUBMITTER: Han KT 

PROVIDER: S-EPMC8064530 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature