Hsp70 affects memory formation and behaviorally relevant gene expression in Drosophila melanogaster.

ABSTRACT: Heat shock proteins, in particular Hsp70, play a central role in proteostasis in eukaryotic cells. Due to its chaperone properties, Hsp70 is involved in various processes after stress and under normal physiological conditions. In contrast to mammals and many Diptera species, inducible members of the Hsp70 family in Drosophila are constitutively synthesized at a low level and undergo dramatic induction after temperature elevation or other forms of stress. In the courtship suppression paradigm used in this study, Drosophila males that have been repeatedly rejected by mated females during courtship are less likely than naive males to court other females. Although numerous genes with known function were identified to play important roles in long-term memory, there is, to the best of our knowle

SUBMITTER: Zatsepina OG 

PROVIDER: S-EPMC8065088 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature