IL-4 rs2243250 polymorphism associated with susceptibility to allergic rhinitis: a meta-analysis.

ABSTRACT:

Objective

The relationship between IL-4 rs2243250 polymorphism and the risk of allergic rhinitis is not clear at present. The present study aims to evaluate the exact association between IL-4 rs2243250 polymorphism and susceptibility to allergic rhinitis by a meta-analysis.

Methods

The studies about IL-4 rs2243250 polymorphism associated with susceptibility to allergic rhinitis were searched using PubMed, Excerpta Medica Database (EMBASE), Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI) and China Wanfang databases. The last search time was on March 1, 2021. Data analysis was performed using Stata 15.0 software.

Results

Nine documents were enrolled, from which 1709 patients with allergic rhinitis were included. Among them, six genotype

SUBMITTER: Jiang F 

PROVIDER: S-EPMC8065178 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature