An Investigation into Mechanical Properties and Printability of Potential Substrates for Inkjet Printing of Orodispersible Films.

ABSTRACT: Inkjet printing is novel approach in drug manufacturing that enables dispensing precise volumes of ink onto substrates. Optimal substrate properties including suitable mechanical characteristic are recognized as crucial to achieve desired dosage form performance upon administration. Identification of relevant quality attributes and their quantification is subject of intensive scientific research. The aim of this work was to explore applicability of different materials as printing substrates and explore contribution of the investigated substrate properties to its printability. Substrates were characterized with regards to uniformity, porosity, disintegration time, mechanical properties and drug dissolution. Experimentally obtained values were mathematically transformed and the obtained resu

SUBMITTER: Turkovic E 

PROVIDER: S-EPMC8066070 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature