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Lagos Bat Virus, an Under-Reported Rabies-Related Lyssavirus.

ABSTRACT: Lagos bat virus (LBV), one of the 17 accepted viral species of the Lyssavirus genus, was the first rabies-related virus described in 1956. This virus is endemic to the African continent and is rarely encountered. There are currently four lineages, although the observed genetic diversity exceeds existing lyssavirus species demarcation criteria. Several exposures to rabid bats infected with LBV have been reported; however, no known human cases have been reported to date. This review provides the history of LBV and summarizes previous knowledge as well as new detections. Genetic diversity, pathogenesis and prevention are re-evaluated and discussed.

SUBMITTER: Coertse J

PROVIDER: S-EPMC8067007 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

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Lagos Bat Virus, an Under-Reported Rabies-Related Lyssavirus.

Coertse Jessica J Geldenhuys Marike M le Roux Kevin K Markotter Wanda W

Viruses 20210329 4

Lagos bat virus (LBV), one of the 17 accepted viral species of the <i>Lyssavirus</i> genus, was the first rabies-related virus described in 1956. This virus is endemic to the African continent and is rarely encountered. There are currently four lineages, although the observed genetic diversity exceeds existing lyssavirus species demarcation criteria. Several exposures to rabid bats infected with LBV have been reported; however, no known human cases have been reported to date. This review provide ...[more]

PMID: 33805487

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