Precision Medicine and Melanoma: Multi-Omics Approaches to Monitoring the Immunotherapy Response.

ABSTRACT: The treatment and management of patients with metastatic melanoma have evolved considerably in the "era" of personalized medicine. Melanoma was one of the first solid tumors to benefit from immunotherapy; life expectancy for patients in advanced stage of disease has improved. However, many progresses have yet to be made considering the (still) high number of patients who do not respond to therapies or who suffer adverse events. In this scenario, precision medicine appears fundamental to direct the most appropriate treatment to the single patient and to guide towards treatment decisions. The recent multi-omics analyses (genomics, transcriptomics, proteomics, metabolomics, radiomics, etc.) and the technological evolution of data interpretation have allowed to identify and understand several

SUBMITTER: Valenti F 

PROVIDER: S-EPMC8067863 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature