Mitigating Future Respiratory Virus Pandemics: New Threats and Approaches to Consider.

ABSTRACT: Despite many recent efforts to predict and control emerging infectious disease threats to humans, we failed to anticipate the zoonotic viruses which led to pandemics in 2009 and 2020. The morbidity, mortality, and economic costs of these pandemics have been staggering. We desperately need a more targeted, cost-efficient, and sustainable strategy to detect and mitigate future zoonotic respiratory virus threats. Evidence suggests that the transition from an animal virus to a human pathogen is incremental and requires a considerable number of spillover events and considerable time before a pandemic variant emerges. This evolutionary view argues for the refocusing of public health resources on novel respiratory virus surveillance at human-animal interfaces in geographical hotspots for emerging

SUBMITTER: Gray GC 

PROVIDER: S-EPMC8068197 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature