Dataset Information

From workplace to home environment: spreading of mouse allergens by laboratory animal workers.

ABSTRACT:

Purpose

Laboratory animal workers (LAW) working with laboratory mice are exposed to mouse allergens (MA). If MA are spread to home environments, this might increase the risk for allergies in LAW and their families. This study aimed to assess 1. whether spreading of MA from workplace to home environment takes place; 2. which factors increase spreading of MA.

Methods

In a cross-sectional study, dust samples were taken on the mattress and seating in homes of LAW (n = 105) and an unexposed comparison group (n = 13). From 89 LAW, additional dust samples were taken from their workplaces. Samples were analysed using Mus m1 ELISA kits [detection limit (DL) 0.2 ng mus m1/ml]. Sociodemographic data, personal history of allergies and cleaning habits, as well as work-related characteristics (LAW only) were assessed by questionnaire. Latent factors were assessed via factor analysis. Tobit models were fitted to analyse the latent factors' contribution to MA spreading.

Results

MA concentration on the seating was significantly higher in home environments of LAW (median = 1.28 ng mus m1/m²) than in the comparison group (median < DL, p = 0.019). The highest workplace MA concentration was found on the floor of the scullery (median = 140,000.00 ng mus m1/m²), followed by hair-covering caps (median = 76.02 ng mus m1/m²). Cage and mouse facility cleaning tasks and infrequent changing of bed linen at home were statistically significantly associated with higher MA concentrations at home.

Conclusions

Spreading of MA from LAW's workplace to their home environment takes place, especially among LAWs involved in cleaning tasks.

SUBMITTER: Kube H

PROVIDER: S-EPMC8068679 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature

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Publications

From workplace to home environment: spreading of mouse allergens by laboratory animal workers.

Kube Hannah H Herrera Ronald R Dietrich-Gümperlein Gisela G Schierl Rudolf R Nowak Dennis D Radon Katja K Wengenroth Laura L Gerlich Jessica J

International archives of occupational and environmental health 20201121 4

<h4>Purpose</h4>Laboratory animal workers (LAW) working with laboratory mice are exposed to mouse allergens (MA). If MA are spread to home environments, this might increase the risk for allergies in LAW and their families. This study aimed to assess 1. whether spreading of MA from workplace to home environment takes place; 2. which factors increase spreading of MA.<h4>Methods</h4>In a cross-sectional study, dust samples were taken on the mattress and seating in homes of LAW (n = 105) and an unex ...[more]

PMID: 33219477

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Project description:BackgroundMany desk-based workers can spend more than half of their working hours sitting, with low levels of physical activity. Workplace neighbourhood built environment may influence workers' physical activities and sedentary behaviours on workdays. We reviewed and synthesised evidence from observational studies on associations of workplace neighbourhood attributes with domain-specific physical activity and sedentary behaviour and suggested research priorities for improving the quality of future relevant studies.MethodsPublished studies were obtained from nine databases (PubMed, Web of Science, PsycINFO, Scopus, Transport Research International Documentation, MEDLINE, Cochrane, Embase, and CINAHL) and crosschecked by Google Scholar. Observational studies with quantitative analyses estimating associations between workplace neighbourhood built environment attributes and workers' physical activity or sedentary behaviour were included. Studies were restricted to those published in English language peer-reviewed journals from 2000 to 2019.ResultsA total of 55 studies and 455 instances of estimated associations were included. Most instances of potential associations of workplace neighbourhood built environment attributes with total or domain-specific (occupational, transport, and recreational) physical activity were non-significant. However, destination-related attributes (i.e., longer distances from workplace to home and access to car parking) were positively associated with transport-related sedentary behaviour (i.e., car driving).ConclusionsThe findings reinforce the case for urban design policies on designing mixed-use neighbourhoods where there are opportunities to live closer to workplaces and have access to a higher density of shops, services, and recreational facilities. Studies strengthening correspondence between the neighbourhood built environment attributes and behaviours are needed to identify and clarify potential relationships.Protocol registrationThe protocol of this systematic review was registered on the International Prospective Register of Systematic Reviews (PROSPERO) on 2 December 2019 (registration number: CRD42019137341 ).

Dataset Information

From workplace to home environment: spreading of mouse allergens by laboratory animal workers.

Purpose

Methods

Results

Conclusions

Publications

From workplace to home environment: spreading of mouse allergens by laboratory animal workers.

Similar Datasets

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